CMR detects a reduction in infarct size and myocardial edema when primary PCI is augmented by Remote Ischemic Conditioning. A randomized trial
نویسندگان
چکیده
Background CMR is the imaging modality of choice to quantify myocardial injury in studies of cardioprotection. Remote ischemic conditioning (RIC), using transient limb ischemia and reperfusion, is a novel therapeutic intervention, which can protect the heart against acute ischemiareperfusion injury (IRI). Whether RIC can reduce myocardial infarct (MI) size, and improve myocardial salvage in ST-segment elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PPCI), is unknown, and was investigated in this randomized control clinical trial using CMR.
منابع مشابه
Myocardium at risk quantified by contrast enhanced steady-state free precession does not differ in extent or severity when comparing patients with ST-elevation myocardial infarction treated with standard reperfusion or postconditioning
Background Accurate quantification of the ischemic myocardium at risk (MaR) in patients with STelevation myocardial infarction (STEMI) is paramount in studies of therapies seeking to reduce infarct size expressed as percent of MaR. Cardiac magnetic resonance (CMR) is an important clinical research tool for determination of MaR and infarct size in the same examination within one week after STEMI...
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OBJECTIVES This study aimed to determine whether remote ischemic conditioning (RIC) initiated prior to primary percutaneous coronary intervention (PPCI) could reduce myocardial infarct (MI) size in patients presenting with ST-segment elevation myocardial infarction. BACKGROUND RIC, using transient limb ischemia and reperfusion, can protect the heart against acute ischemia-reperfusion injury. ...
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