Effect of Ethanol Leaf-Extract of Annona muricata on Serum Total Protein and Albumin Concentrations in Albino Rats

Annona muricata has been reported to treat several ailments such as headaches, insomnia, cystitis, liver problems, diabetes, hypertension, inflammation, dysentery, among others. The present study investigated the effect of ethanol leaf-extract of Annona muricata on serum total protein and albumin concentrations in albino rats using spectrophotometric methods. Twenty albino rats were randomly assigned into four groups (A, B, C andD) with five rats in each. Doses of 200mg/kg, 400mg/kg and600mg/kg body weight of the extract were administered to animals in groups B, C andD respectively via oral intubation twice daily for fourteen consecutive days while group A served as control and received no extract. Blood of the animals were collected on the 15 day following the last day of administration through heart puncture. There was no significant effect th (p > 0.05) on serum total protein and albumin concentrations except at the dose of 600mg/kg.