[Multiple pulmonary nodules and amiodarone. KL-6 as a new diagnostic tool].

نویسندگان

  • Enrique Bernal Morell
  • Antonio Hernández Madrid
  • Irene Marín Marín
  • Rebeca Rodríguez Pena
  • María C González Gordaliza
  • Concepción Moro
چکیده

Pulmonary toxicity is an infrequent but serious adverse event in patients treated with amiodarone. The main problem at present is that we lack the necessary tools to detect this event or predict which patients will develop pulmonary toxicity. Serum Krebs von den Lungen-6 (KL-6) has been previously recognized as a marker for the activity of diffuse interstitial lung disease. We describe a patient with pulmonary toxicity due to amiodarone with increased blood levels of this new marker, and discuss the clinical usefulness of this new diagnostic tool.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Amiodarone-induced pulmonary toxicity

Amiodarone-induced pulmonary toxicity is a critical and potentially fatal side effect of amiodarone. Our study was designed to reveal its clinical features, including KL-6, as an interstitial marker. The medical records of eight patients (five men and three women) with amiodarone-induced pulmonary toxicity, who had been referred to our hospital, were examined. The mean age at the initiation of ...

متن کامل

Usefulness to quantify serum KL-6 levels to follow up uveitic patients with sarcoidosis

Background: KL-6 is a human glycoprotein secreted by type II alveolar cells in lung, and its serum levels increase in pneumonia of various causes. We previously reported that serum KL-6 levels in the uveitis patients with sarcoidosis were significantly higher than that of other uveitis and healthy controls. And combined measurement of serum KL-6 and angiotensin converting enzyme (ACE) was usefu...

متن کامل

تظاهرات توراکوسکوپیک توبرکلوز پلور

Background & Aims: Pleural effusion is the most common form of extra-pulmonary tuberculosis. With the advancement of endoscopic techniques, thoracoscopy has been identified as a diagnostic procedure for Pleural TB. The aim of this study was to evaluate the thoracoscopic manifestations of pleural tuberculosis and its association with the pathological findings of pleural tuberculosis. Materials ...

متن کامل

Protective Effect of Caffeic Acid Phenethyl Ester (CAPE) on Amiodarone-Induced Pulmonary Fibrosis in Rat

Treatment with amiodarone, a commonly prescribed antidysrhythmic agent, is associated with pulmonary fibrosis (PF) which is a commonly progressive and untreatable dieases. Caffeic acid phenethyl ester (CAPE) is a phenolic antioxidant and an active anti-inflammatory, anticancer, antimicrobial and antioxidant component of propolis (bee glue; a resinous hive product collected by honey bees). In th...

متن کامل

Pulmonary Nodular Lymphoid Hyperplasia: A Rare Case Mimicking Malignancy

Pulmonary nodular lymphoid hyperplasia (PNLH) is a reactive lymphoid proliferation manifesting as multiple solitary nodules or localized infiltrates in the lungs. It is a type of benign lymphoproliferative disease that can affect the lungs. We present the case of a 41-year-old female patient with respiratory symptoms such as productive cough, left chest pain, and dyspnea. Imaging findings revea...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Revista espanola de cardiologia

دوره 58 4  شماره 

صفحات  -

تاریخ انتشار 2005