Novel use of apremilast for adjunctive treatment of recalcitrant pyoderma gangrenosum
نویسندگان
چکیده
PG: pyoderma gangrenosum TNF: tumor necrosis factor Pyoderma gangrenosum (PG) is a rare, neutrophilic, ulcerative dermatosis without a therapeutic gold standard. Vegetative PG is a chronic superficial variant, which is more indolent and typically responds well to treatment. Here we describe a patient with a 3-year history of uncharacteristically recalcitrant vegetative PG who responded to apremilast.
منابع مشابه
Adalimumab Therapy for Recalcitrant Pyoderma Gangrenosum
OBJECTIVE To describe a patient with treatment-refractory pyoderma gangrenosum and the outcome of a novel therapeutic approach. METHODS Case report and review of the literature. RESULTS A patient with inflammatory bowel disease developed severe pyoderma gangrenosum while receiving treatment with the chimeric anti-TNF-alpha antibody infliximab. Despite subsequent trials of numerous immunosup...
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