Aqueous asymmetric cyclopropanation reactions in polymersome membranes.
نویسندگان
چکیده
Copper-bis(oxazoline) complexes have been immobilised in the hydrophobic domain of a polymersome membrane to perform asymmetric cyclopropanation reactions in aqueous media with enhanced conversions and enantioselectivities.
منابع مشابه
Cross-linked polymersomes as nanoreactors for controlled and stabilized single and cascade enzymatic reactions.
Polymeric vesicles or polymersomes are one of the supramolecular entities at the leading edge of synthetic biology. These small compartments have shown to be feasible candidates as nanoreactors, especially for enzymatic reactions. Once cross-linked and equipped with a pH sensitive material, the reaction can be switched off (pH 8) and on (pH 6) in accordance with the increased permeability of th...
متن کاملDesigning new ligands: asymmetric cyclopropanation by Cu(i) complexes based on functionalised pyridine-containing macrocyclic ligands.
The synthesis and characterisation of copper(i) complexes, including two crystal structures of the new chiral pyridine-containing macrocyclic ligands (PC-type), and their use as catalysts in asymmetric cyclopropanation reactions are reported.
متن کاملSynthesis of New Optically Active 3.5-DinitrosalicyloxazoIines
In the first homogeneous enantioselective catal ysis, a cyclopropanation reaction, Nozaki et al. used copper complexes of optically active salicylaldimines as the catalysts [2]. Systematic studies with such Schiff base complexes enabled Aratani et al. to achieve high optical yields in asymmetric cyclo propanation reactions [3,4], An industrial appli cation is the synthesis of a precursor of ...
متن کاملMulticompartment polymersome gel for encapsulation
We introduce an approach that combines the concepts of emulsiontemplating and dewetting for fabricating polymersomes with a large number of compartments. The resultant polymersome gel behaves as a gel-like solid, but is a true vesicle suspended in an aqueous environment. Due to the thin membranes that separate the compartments, the polymersome gels have a high volume fraction of internal phase ...
متن کاملAsymmetric inter- and intramolecular cyclopropanation of alkenes catalyzed by chiral ruthenium porphyrins. Synthesis and crystal structure of a chiral metalloporphyrin carbene complex.
Extensive investigations of asymmetric intermolecular cyclopropanation of terminal alkenes with diazoacetates catalyzed by ruthenium porphyrin [Ru(P*)(CO)(EtOH)] (1, H2P = 5,10,15,20-tetrakis[(1S,4R,5R,8S)-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-yl]porphyrin) and the application of catalyst 1 to asymmetric intramolecular cyclopropanation of allylic or homoallylic diazoacetates a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 50 31 شماره
صفحات -
تاریخ انتشار 2014