Experimental investigation of microbubble response to ultrasonic pulses used in therapeutic applications
نویسندگان
چکیده
Research interest in the area of ultrasound contrast agents is shifting towards therapeutic applications such as targeted drug delivery, gene and DNA transfection [1], sonothrombolysis [2], and sonoporation [3]. To date however, the microbubble response to therapeutic-type excitations has not been studied in detail and it is not well understood. Often the conditions used in published works are simply a case of trial and error during which the microbubbles are subjected to pulses ranging from a few cycles [1] up to several thousand cycles [4].
منابع مشابه
Proceedings of Meetings on Acoustics
Interest in microbubbles as agents for therapeutic and quantitative imaging applications in biomedical ultrasound has increased the need for their accurate modelling. However, effects such as gas diffusion, the properties of the shell and changes in bubble behaviour under repeated exposure to ultrasound pulses are still not well understood. A revised equation for microbubble motion is proposed ...
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