Inkjet Printing of Doxycycline Loaded Transdermal Film for Wound Infection

Oral drug delivery is the most common route for its convenient and easy administration in Bangladesh. But, it has several limitations such as the hepatic first pass effect, enzymatic degradation and inactivation in gastric environment. Another, hypodermic needles are painful, less convenient and expensive for patients [1]. However, current drug delivery technologies are facilitated by either (trans) mucosal [2-5], or transdermal [6] delivery system. The mucosal route of drug administration has some additional advantages, showing the low enzymatic activity, painless delivery that improved patient compliance, easy termination of dosage form, option to incorporate permeation enhancer and flexibility in developing fast or controlled release systems for systemic or non-systemic effect [7-9]. Moreover, it can be beneficial for patients who have complexity in swallowing tablets or capsules. Also, the drug release is characteristically related to the physicochemical properties of drugs in the aqueous medium [10].