Letter to the Editor: Serum anti-Müllerian hormone levels and phenotypes of polycystic ovary syndrome
نویسندگان
چکیده
Dear Editor: The recent report on serum anti-Müllerian hormone (AMH) levels and phenotypes of polycystic ovary syndrome is very interesting [1]. Hwang et al. [1] concluded that “high serum AMH levels cannot predict the phenotype of polycystic ovary syndrome (PCOS) and metabolic disturbances in PCOS patients in the non-obese group”. Notably, the results from this work are totally different from those of a recent report from Turkey [2]. Sahmay et al. [2] found that “AMH levels correlate best with polycystic ovarian mor phology (PCOM)”. In fact, the null relationship in the present report might be due to poor grouping and few subjects. The fact that the AMH is related to ovarian morphology should support the proposed correlation between AMH levels and PCOM phenotype [3].
منابع مشابه
Relationship between Serum Levels of Anti-Mullerian Hormone, Adiponectin and Oxidative Stress Markers in Patients with Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Anti-Mullerian hormone (AMH) is a valid indicator of ovarian function and is used for PCOS diagnosis. Some studies have shown that adipokines affect the synthesis of AMH, and therefore they are somehow related in function. The aim of the present study was to determine the relationshi...
متن کاملP-85: Effect of Metformin on Anti-Mullerian Hormone (AMH) Level in Women with Infertility and Polycystic Ovary Syndrome
Background Women with PCOS have increased AMH levels due to accumulated preantral and small antral in follicles. Ovulation improvement following decrease in levels of AMH could accure in these patients. The purpose of this study was to evaluate the effect of metformin on anti-Mullerian hormone levels in women with polycystic ovary syndrome and infertility MaterialsAndMethods This randomized cli...
متن کاملThe Author Response: Serum anti-Müllerian hormone levels and phenotypes of polycystic ovary syndrome
Reply: We recently published an original article entitled “Can high serum Anti-Müllerian hormone (AMH) levels predict the phenotypes of polycystic ovary syndrome (PCOS) and metabolic disturbances in PCOS patients?” [1]. There are numerous reports on high serum AMH levels in patients with PCOS, and their serum AMH levels are much variable. We were curious about the possibility that high serum AM...
متن کاملSerum anti-Mullerian hormone levels in the main phenotypes of polycystic ovary syndrome.
OBJECTIVE To characterize the difference in circulating anti-Müllerian hormone (AMH) levels between the main polycystic ovary syndrome (PCOS) phenotypic groups and evaluate the role of AMH in predicting the severity of PCOS. STUDY DESIGN Cross-sectional, retrospective study. A total of 251 women were divided into four groups based on the main features of PCOS, as follows: Group 1 (polycystic ...
متن کاملDifferentiation between polycystic ovary syndrome and polycystic ovarian morphology by means of an anti-Müllerian hormone cutoff value
BACKGROUND/AIMS Although increased serum anti-Müllerian hormone (AMH) level has been suggested to be a surrogate marker of polycystic ovarian morphology (PCOM), its association with polycystic ovary syndrome (PCOS) is controversial, and its diagnostic value has not been determined. We aimed to observe the relationship between the AMH level and PCOS phenotypes and to determine the optimal cutoff...
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