Author's response to reviews Title: Expression of a novel short isoform of the kidney disease protein podocin in human kidney Authors:

نویسندگان

  • Linus A Völker
  • Eva-Maria Schurek
  • Barbara A Schutte
  • Tobias Lamkemeyer
  • Denise Ungrue
  • Bernhard Schermer
  • Thomas Benzing
  • Martin Höhne
چکیده

Linus A Völker ([email protected]) Eva-Maria Schurek ([email protected]) Judit Tax ([email protected]) Barbara A Schutte ([email protected]) Tobias Lamkemeyer ([email protected]) Denise Ungrue ([email protected]) Bernhard Schermer ([email protected]) Thomas Benzing ([email protected]) Martin Höhne ([email protected])

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Characterization of a short isoform of the kidney protein podocin in human kidney

BACKGROUND Steroid resistant nephrotic syndrome is a severe hereditary disease often caused by mutations in the NPHS2 gene. This gene encodes the lipid binding protein podocin which localizes to the slit diaphragm of podocytes and is essential for the maintenance of an intact glomerular filtration barrier. Podocin is a hairpin-like membrane-associated protein that multimerizes to recruit lipids...

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Characterization of a short isoform of the kidney protein

37 Background/Aims: Steroid resistant nephrotic syndrome is a severe hereditary disease often caused 38 by mutations in the NPHS2 gene. This gene encodes the lipid binding protein podocin which localizes 39 to the slit diaphragm of podocytes and is essential for the maintenance of an intact glomerular 40 filtration barrier. Podocin is a hairpin-like membrane-associated protein that multimerizes...

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Alteration of protein expression pattern of vascular endothelial growth factor (VEGF) from soluble to Title: cell-associated isoform during tumourigenesis

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تاریخ انتشار 2013