Chapter 11 Neuroreceptor Imaging
نویسنده
چکیده
I.-Y. Choi and R. Gruetter (eds.), Neural Metabolism In Vivo, Advances in Neurobiology 4, DOI 10.1007/978-1-4614-1788-0_11, © Springer Science+Business Media, LLC 2012 Abstract Neuroreceptor imaging using PET and SPECT has contributed to clinical neuroscience and diagnosis (e.g. neurodegenerative disease and antipsychotic-drug receptor occupancy). Recent advances in dedicated PET and SPECT instrumentation, disease-specifi c radioligands, and image analysis techniques contributed to the further development of this fi eld and its widespread application. In this chapter, we introduce the basis concepts of neuroreceptor imaging using typical radioligands, standard modeling and analysis techniques and discuss future research opportunities in the fi eld.
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