Interactive Poster: Effective Display of Conserved Domains on a Multiple Sequence Alignment

نویسندگان

  • Andrew D. Lindeman
  • Susan M. Bridges
چکیده

Multiple sequence alignment (MSA) is used to explore the similarity of several related protein sequences by providing a near optimal alignment of the characters in each sequence. Biologists require effective visualization of these alignments as part of their analysis. Although tools such as Jalview have been developed that provide a detailed view of different aspects of the alignments and metadata such as conserved domains, these tools do not automatically download the metadata via the web and the alignment cannot be viewed at varying levels of detail. We have developed a prototype MSA visualization application that focuses on simultaneous display of characteristics of the alignment and automatically downloaded metadata such as conserved domains, and allows the user to view the information at different levels of detail to enable easy recognition of interesting patterns for further analysis. CR

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تاریخ انتشار 2011