Two new cytotoxic acetogenins from Annona squamosa.

نویسندگان

  • Hai-Jun Yang
  • Xiang Li
  • Ning Zhang
  • Jian-Wei Chen
  • Ming-Yan Wang
چکیده

Two new annonaceous acetogenins named as squamostanin-A and squamostanin-B were isolated from 95% EtOH extract of the seeds of Annona squamosa. Their structures were determined by spectroscopic method, and their cytotoxicities were evaluated using MTT method.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata.

Three new monotetrahydrofuran annonaceous acetogenins, muricin H (1), muricin I (2), and cis-annomontacin (3), along with five known acetogenins, annonacin, annonacinone, annomontacin, murisolin, and xylomaticin, were isolated from the seeds of Annona muricata. Additionally, two new monotetrahydrofuran annonaceous acetogenins, cis-corossolone (4) and annocatalin (5), together with four known on...

متن کامل

Anthelmintic acetogenin from Annona squamosa L. Seeds.

Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml(-1). The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis.

متن کامل

Five new monotetrahydrofuran ring acetogenins from the leaves of Annona muricata.

Bioactivity-directed fractionation of the leaves of Annona muricata resulted in the isolation of annopentocins A (1), B (2), and C(3), and cis- and trans-annomuricin-D-ones (4, 5). Compounds 1-3 are the first acetogenins reported bearing a mono-tetrahydrofuran (THF) ring with one flanking hydroxyl, on the hydrocarbon side, and another hydroxyl, on the lactone side, that is one carbon away from ...

متن کامل

Phytochemical Screening and Cytotoxic Activity of Two Extracts from Seeds of Lebanese Annona squamosa L

Phytochemical Screening and Cytotoxic Activity of Two Extracts from Seeds of Lebanese Annona squamosa L Abbas Sabbah , Mohamad Nasser, Akram Hijazi, Hassan Rammal 1, , Ghassan Nasser 1 Basic Sciences department, Faculty of Agronomy, Lebanese University, Lebanon 2 Doctoral School of Science and Technology, Platform for Research and Analysis in Environmental Sciences (PRASE), Lebanese University,...

متن کامل

Screening of biological actives extracts from Annona squamosa

The aim of the present study is to focus on the cytotoxicity and antimicrobial activities from Annona squamosa plant seed extracts. The plant A. squamosa seed was extracted with various solvents like chloroform, methanol, hexane, petroleum ether and acetone. The antimicrobial activities of all these extracts were determined by disc diffusion method against Pseudomonas aeruginosa, Proteius vulga...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of Asian natural products research

دوره 11 3  شماره 

صفحات  -

تاریخ انتشار 2009