Antimicrobial resistance of invasive pneumococci in Finland in 1999-2000.
نویسندگان
چکیده
The resistance patterns and macrolide resistance mechanisms of 910 Finnish invasive pneumococci isolated during 1999 and 2000 were studied. Macrolide resistance was detected in 6.9% of isolates. Penicillin resistance was detected in 1.5% of isolates, and penicillin intermediate resistance was detected in 4.0% of isolates. Active macrolide efflux, mediated by the mef(A) gene, was the most common macrolide resistance mechanism. Four macrolide-resistant isolates had mutations in rRNA or ribosomal protein L22.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 47 6 شماره
صفحات -
تاریخ انتشار 2003