Cytomegalovirus Induced Neonatal Cholestasis: A success Story
نویسندگان
چکیده
Neonatal cholestasis is a prolonged elevation of the serum levels of conjugated bilirubin beyond the first 14 days of life. Commonest etiologies include extrahepatic conditions like biliary atresia, intrahepatic like congenital malformations, infections and inborn errors of metabolism. TORCH infections constitute 22% cases of neonatal hepatitis, of which Cytomegalovirus is the commonest agent. Ganciclovir and its prodrug valganciclovir are recommended in the management of Cytomegalovirus infection. We, hereby report a 2 month old child, a case of Cytomegalovirus induced neonatal cholestasis with marked improvement in clinical and biochemical parameters, post treatment with intravenous ganciclovir.
منابع مشابه
Infection by cytomegalovirus in patients with neonatal cholestasis.
BACKGROUND Neonatal cholestasis syndrome with an intra or extrahepatic origin has been associated to viral infections. The participation of the cytomegalovirus in the etiopathogenesis of neonatal hepatitis has been already known for some time, but only recently there have been indications that this virus may be one of the possible etiological factors for extrahepatic biliary atresia. AIMS To ...
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