Arya Mani , Disease and Metabolic Risk Factors Mutation in a Family with Early

نویسنده

  • Arya Mani
چکیده

http://www.sciencemag.org/cgi/content/full/315/5816/1278 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/315/5816/1278/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.sciencemag.org/cgi/content/full/315/5816/1278#related-content http://www.sciencemag.org/cgi/content/full/315/5816/1278#otherarticles , 8 of which can be accessed for free: cites 26 articles This article 14 article(s) on the ISI Web of Science. cited by This article has been http://www.sciencemag.org/cgi/content/full/315/5816/1278#otherarticles 10 articles hosted by HighWire Press; see: cited by This article has been http://www.sciencemag.org/cgi/collection/genetics Genetics : subject collections This article appears in the following

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A form of the metabolic syndrome associated with mutations in DYRK1B.

BACKGROUND Genetic analysis has been successful in identifying causative mutations for individual cardiovascular risk factors. Success has been more limited in mapping susceptibility genes for clusters of cardiovascular risk traits, such as those in the metabolic syndrome. METHODS We identified three large families with coinheritance of early-onset coronary artery disease, central obesity, hy...

متن کامل

Prevalence of Metabolic Syndrome in Patients with Periodontal Disease

Background & Aims: Metabolic syndrome is composed of interrelated cardiovascular and cardiometabolic risk factors. Moreover, recent researches have illustrated the association of systemic diseases and periodontitis. Thus, the early diagnosis of this syndrome, as a cardiometabolic risk factor, seems necessary. The aim of this study was to evaluate the prevalence of metabolic syndrome in patients...

متن کامل

Low-Density Lipoprotein Receptor (LDLR) Family Orchestrates Cholesterol Homeostasis

The LDLR family of proteins is involved in lipoproteins trafficking. While the role of LDLR in cardiovascular disease has been widely studied, only recently the role of other members of the LDLR proteins in lipoprotein homeostasis and atherosclerosis has emerged. LDLR, VLDLR, and LRPs bind and internalize apoE- and apoB-containing lipoprotein, including LDL and VLDL, and regulate their cellular...

متن کامل

شناسایی جهش های جدید در اگزون 11 ژنBRCA1 در بیماران مبتلا به سرطان پستان ارثی

Introduction: Breast cancer is the most common malignancy in women worldwide. BRCA1 is a tumor suppressor gene that is involved in DNA-damage repair. One of the significant risk factors of breast cancer is the family history. BRCA1 gene consists of 24 exons that encode a protein with 1863 amino acids. Exon 11 is the largest exons and most of the disease-linked mutations have been found in it. I...

متن کامل

Comparing PET metabolic parameters with clinicopathological factors in predicting onset of early recurrence in recently diagnosed hepatocellular carcinoma

Introduction: Early recurrence of hepatocellular carcinoma (HCC) is a major risk factor affecting survival even after hepatectomy. Many clinical, biochemical parameters and pathological grading like fibrosis 1 index have been used for risk stratifying HCC. However not many studies have combined all of them. It is therefore important to risk stratify HCC especially with newer PE...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008