Commentary: Disease modelling to inform policy on male circumcision for HIV prevention.

نویسندگان

  • Ronald H Gray
  • Maria J Wawer
  • Godfrey Kigozi
  • David Serwadda
چکیده

Progression to symptomatic disease in people infected with HIV-1 in rural Uganda: prospective cohort study. BMJ 2002;324:193–96. 30 Bobat R, Moodley D, Coutsoudis A, Coovadia H, Gouws E. The early natural history of vertically transmitted HIV-1 infection in African children from Durban, South Africa. Ann Trop Paediatr 1998;18: 187–96. 31 Klasse PJ, Shattock R, Moore JP. Antiretroviral drugbased microbicides to prevent HIV-1 sexual transmission. Annu Rev Med 2008;59:455–471. 32 Agot KE, Kiarie JN, Nguyen HQ, Odhiambo JO, Onyango TM, Weiss NS. Male circumcision in Siaya and Bondo districts, Kenya: prospective cohort study to assess behavioral disinhibition following circumcision. J Acquir Immune Defic Syndr 2007;44:66–70.

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Three recent randomised controlled trials [1–3] in Kenya, South Africa, and Uganda have confirmed previous observational studies [4] and ecological experience [5] and demonstrated beyond reasonable doubt that male circumcision performed by well-trained medical professionals reduces the risk of men acquiring HIV through female-to-male transmission by approximately 60% [5,6]. Furthermore, results...

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Male Circumcision for HIV Prevention in High HIV Prevalence Settings: What Can Mathematical Modelling Contribute to Informed Decision Making? UNAIDS/WHO/SACEMA Expert Group on Modelling the Impact and Cost of Male Circumcision for HIV

Three recent randomised controlled trials [1–3] in Kenya, South Africa, and Uganda have confirmed previous observational studies [4] and ecological experience [5] and demonstrated beyond reasonable doubt that male circumcision performed by well-trained medical professionals reduces the risk of men acquiring HIV through female-to-male transmission by approximately 60% [5,6]. Furthermore, results...

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Male Circumcision for HIV Prevention in High HIV Prevalence Settings: What Can Mathematical Modelling Contribute to Informed Decision Making? UNAIDS/WHO/SACEMA Expert Group on Modelling the Impact and Cost of Male Circumcision for HIV

and Cost , C; Hargrove, J; Williams, B; Abu-Raddad, L; Auvert, B; Bollinger, L; Dorrington, R; Ghani, A; Gray, R; Hallett, T; Kahn, JG; Lohse, N; Nagelkerke, N; Porco, T; Schmid, G; Stover, J; Weiss, H; Welte, A; White, P; White, R; ) (2009) Male circumcision for HIV prevention in high HIV prevalence settings: what can mathematical modelling contribute to informed decision making? PLoS medicine...

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عنوان ژورنال:
  • International journal of epidemiology

دوره 37 6  شماره 

صفحات  -

تاریخ انتشار 2008