Florence Robert - Gangneux and Marie - Laure Dardé for Toxoplasmosis Epidemiology of and Diagnostic Strategies
نویسندگان
چکیده
منابع مشابه
Epidemiology of and diagnostic strategies for toxoplasmosis.
The apicomplexan parasite Toxoplasma gondii was discovered a little over 100 years ago, but knowledge of its biological life cycle and its medical importance has grown in the last 40 years. This obligate intracellular parasite was identified early as a pathogen responsible for congenital infection, but its clinical expression and the importance of reactivations of infections in immunocompromise...
متن کاملGenotype of 88 Toxoplasma gondii isolates associated with toxoplasmosis in immunocompromised patients and correlation with clinical findings.
We report the genotyping analysis of Toxoplasma gondii isolates in samples collected from 88 immunocompromised patients, along with clinical and epidemiological data. Most of these samples were collected in France during the current decade by the Toxoplasma Biological Resource Center. Lack of specific anti-Toxoplasma treatment, pulmonary toxoplasmosis, and involvement of multiple organs were th...
متن کاملGenetic analysis of the diversity in Toxoplasma gondii.
More than 50 different genetic markers are now available for Toxoplasma gondii isolate typing. For most of them, allelic polymorphism is low (2 to 4 alleles). A few markers, more polymorphic, can be used to fingerprint isolates for epidemiological studies. Phylogenetic analysis detects 2 main groups in Toxoplasma population. Group 2 is genetically heterogeneous. From a practical point of view, ...
متن کاملMolecular diagnosis of toxoplasmosis in immunocompromised patients.
PURPOSE OF REVIEW Toxoplasmosis in immunocompromised patients is associated with a high mortality rate. Molecular techniques are important tools to diagnose acute disease in immunocompromised patients, but there are various methods with variable efficiency. Some of them have been validated for the diagnosis of congenital toxoplasmosis, but the impact of their use has not been evaluated in immun...
متن کاملSevere Acquired Toxoplasmosis Caused by Wild Cycle of Toxoplasma gondii, French Guiana
From 1998 through 2006, 44 cases of severe primary toxoplasmosis were observed in French Guiana in immunocompetent adults. Toxoplasma gondii isolates exhibited an atypical multilocus genotype. Severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii circulating in a forest-based cycle.
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