Miller Fisher Syndrome – An Atypical Clinical Presentation

Miller Fisher Syndrome (MFS) is an acquired disease of nervous system which is considered as a rare variant of Guillain-Barré Syndrome (GBS). Collier first described in 1932 as a variant of the Guillain-Barre syndrome with the triad of ataxia, areflexia and ophthalmoplegia. Charles Miller Fisher in 1956 described 3 patients with the symptoms of sluggish pupillary reflexes, acute external ophthalmoplegia, ataxia and areflexia [1], who were recovered spontaneously. MFS also has rarer variants. Here we are presenting a case of MFS having distal paresthesias, weakness of all four limbs, ptosis along with ataxia, areflexia, ophthalmoplegia conservatively managed. The patient gradually improved in symptoms including power, ataxia, ophthalmoplegia without intravenous immunoglobulin. After 20 days the patient was discharged from hospital with complete recovery.