Prophylactic sclerotherapy for varices.

نویسندگان

  • D W Bullimore
  • P Foster
چکیده

cutaneous malignancy is complex. Current models suggest, however, that ozone depletion may cause a more rapid increase in melanoma than in non-melanoma skin cancer.10 This is because short episodes of intense and burning ultraviolet exposure are linked to melanoma, whereas nonmelanoma skin cancer is associated with the lifetime build up of exposure to ultraviolet. To quantify changes in incidence and risk of skin cancer caused by the depletion of ozone is clearly important, but changes in holiday and clothing habits may make it impossible to attribute a percentage of the increased cancers to this depletion. What action is required? Firstly, more nations should set up monitoring equipment at various locations to record ultraviolet changes through the entire ultraviolet A, ultraviolet B, and ultraviolet C portions of the spectrum. Secondly, those who have recently spent a long time in Antarctica should be observed for cutaneous malignancies. The outdoor protection needed in the Antarctic may well, however, have effectively protected people against ultraviolet." Resident fauna such as the Emperor penguins may show ocular damage induced by ultraviolet and might merit a field study. Plankton in the surface waters around Antarctica may for the first time in their evolutionary history experience ultraviolet B or ultraviolet C. Lastly, the Montreal convention, signed last September, should be strengthened. 2 The convention aims at reducing the production of chlorofluorocarbons by halfby the end of the 1990s. This is too little and too late. A drastic reduction of chlorofluorocarbon production is needed as soon as possible to prevent an environmental problem becoming an environmental catastrophe. RONA M MAcKIE Professor of Dermatology, University of Glasgow, Glasgow GIl 6NU MICHAEL J RYCROFT Head, Upper Atmospheric Sciences Division, British Antarctic Survey, Cambridge CB3 OET

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منابع مشابه

A meta-analysis of prophylactic endoscopic sclerotherapy for esophageal varices.

OBJECTIVES A number of randomized clinical trials of prophylactic sclerotherapy have been carried out with different results. The main objective of this study was to determine if the literature provides evidence that prophylactic sclerotherapy increases the survival rate of patients with esophageal varices. METHODS Meta-analysis was used to evaluate the effect of prophylactic sclerotherapy on...

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Prophylactic Sclerotherapy for Oesophageal Varices

The Veterans Affairs Cooperative Variceal Sclerotherapy Group. (1991) Prophylactic sclerotherapy for esophageal varices in men with alcoholic liver disease. The New England Journal of Medicine; 324: 1779-1784. Background. Sclerotherapy is an effective treatment for bleeding esophageal varices in patients with alcoholic liver disease. It has also been suggested that sclerotherapy might be effect...

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Does Prophylactic Endoscopic Sclerotherapy Prevent Variceal Bleeding Or Not? A Question of Experimental Design

l/an Thiel, D. H., Dindzans, V. J., Schade, R. R., Rabinovitz, M. and Gavaler, J. S. (1993) Prophylactic versus emer#ency sclerotherapy of lar#e esopha#eal varices prior to liver transplantation. Di#estive Diseases and Sciences; 38 1505-1510 From January 1985 through July 1987, adult patients accepted for liver transplantation with large esophageal varices were enrolled in a study evaluating th...

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Complications of sclerotherapy for esophageal varices in liver transplant candidates.

ENDOSCOPIC sclerotherapy as the initial form of therapy for bleeding esophageal varices is considered to be the treatment of choice in many centers. While bleeding is usually effectively controlled, \,2 the long-term prognosis for such patients remains poor3 ,4 since progressive hepatic deterioration often precipitated by the bleeding episode frequently leads to an early death. In an attempt to...

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Prophylactic Sclerotherapy: Yes or No!

(1994) Prophylactic sclerotherapy for esophageal varices: Long-term results of a prospective study. Endoscopy; 26: 729-733. Controlled trials of endoscopic sclerotherapy for the prevention of the first variceal hemorrhage have given controversial results. We continued a previously reported study and randomly assigned 141 patients with esophageal varics and no prior gastrointestinal bleeding to ...

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Prophylactic endoscopic sclerotherapy of large esophagogastric varices in infants with biliary atresia.

BACKGROUND Esophageal varices-related GI bleeding occurs frequently and early in life in children with biliary atresia and it may be life threatening. OBJECTIVE We report the results of prophylactic sclerotherapy in 13 infants with biliary atresia and large varices. PATIENTS Mean age was 13 months, mean weight was 8.2 kg, mean total serum bilirubin was 258 mumol/L, and mean prothrombin time...

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عنوان ژورنال:
  • BMJ

دوره 297 6645  شماره 

صفحات  -

تاریخ انتشار 1988