Acquired immune-deficiency syndrome with focal onset of Mycobacterium avium infection displaying a histological/genetic pattern of disseminated mycobacteria.

نویسندگان

  • Kenji Hibiya
  • Masao Tateyama
  • Masaki Niimi
  • Hiromitsu Teruya
  • Yousuke Karimata
  • Jun Hirai
  • Yoshihiro Tokeshi
  • Shusaku Haranaga
  • Daisuke Tasato
  • Hideta Nakamura
  • Yasushi Ihama
  • Attitya Haroon
  • Haley L Cash
  • Futoshi Higa
  • Akira Hokama
  • Kenji Ogawa
  • Jiro Fujita
چکیده

A 66-year-old man with human immunodeficiency virus (HIV) infection was admitted for treatment of Pneumocystis pneumonia. Upon admission, a tumor mass adjacent to the thoracic descending aorta was revealed on computed tomography. Histology revealed an exudative granuloma with histiocytes packed with numerous acid-fast bacilli. Mycobacterium avium was isolated from the tissue. A genetic examination of the isolates demonstrated this strain to be located in the cluster consisting of strains that cause systemic infection. The patient's baseline CD4+ cell count was 9/μL and the HIV-RNA viral load was 43,800 copies/mL. This case suggests the possibility of a localized onset of disseminated M. avium infection.

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عنوان ژورنال:
  • Internal medicine

دوره 51 21  شماره 

صفحات  -

تاریخ انتشار 2012