Clinical Policy Bulletin: Remote Ischemic Conditioning
ثبت نشده
چکیده
Aetna considers remote ischemic conditioning experimental and investigational for the treatment of aneurysmal subarachnoid hemorrhage, myocardial infarction, primary graft dysfunction following lung transplantation, spinal cord injury, traumatic brain injury, and other indications (e.g., for cardiac, cognitive, pulmonary and renal protection during cardiac surgery, endovascular aneurysm repair, spinal surgery, or stroke; not an all-inclusive list) because its effectiveness has not been established.
منابع مشابه
Novel renoprotection methods by local and remote conditioning
*Corresponding author: Prof. Mehri Kadkhodaee, Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. E-mail: [email protected] Implication for health policy/practice/research/medical education: The possibility to create resistance against ischemic injury through ‘organ conditioning’ is an area of increasing interest. The remote ischemic condit...
متن کاملThe role of nitric oxide in the protective action of remote ischemic per-conditioning against ischemia/reperfusion-induced acute renal failure in rat
Objective(s): We investigated the role of nitric oxide (NO) in the protective effects of remote ischemic per-conditioning (rIPerC) on renal ischemia/reperfusion (I/R) injury in male rats. Materials and Methods: I/R treatment consisted of 45 min bilateral renal artery ischemia and 24 hr reperfusion interval. rIPerC was performed using four cycles of 2 min occlusions of the left femoral artery an...
متن کاملThe application of remote ischemic conditioning in cardiac surgery
Perioperative myocardial ischemia and infarction are the leading causes of morbidity and mortality following anesthesia and surgery. The discovery of endogenous cardioprotective mechanisms has led to testing of new methods to protect the human heart. These approaches have included ischemic pre-conditioning, per-conditioning, post-conditioning, and remote conditioning of the myocardium. Pre-cond...
متن کاملProtective role of remote ischemic per-conditioning in acute renal injury induced by ischemia reperfusion via TLR-4 and TNF-α signaling pathway in rats
sIntroduction: Acute kidney injury (AKI) induced by ischemia-reperfusion (I / R) of the kidney as an inflammatory process in which multiple inflammatory factors are involved. Recently, one of the modalities of inflammation in AKI is Remote Ischemic Per-Conditioning (RIPerC). Materials and Methods: In this study, bilateral renal artery and vein occlusion were done for 45 minute and reperfusion a...
متن کاملRemote Ischemic Conditioning to Protect against Ischemia-Reperfusion Injury: A Systematic Review and Meta-Analysis
BACKGROUND Remote ischemic conditioning is gaining interest as potential method to induce resistance against ischemia reperfusion injury in a variety of clinical settings. We performed a systematic review and meta-analysis to investigate whether remote ischemic conditioning reduces mortality, major adverse cardiovascular events, length of stay in hospital and in the intensive care unit and biom...
متن کامل