Successful treatment of Trichosporon mucoides infection with lipid complex amphotericin B and 5-fluorocytosine.
نویسندگان
چکیده
Infections in immunocompromised children can stem from bacteria, fungi, viruses, or protozoa, but most importantly, from the host's endogenous bacterial flora. Disseminated infection caused by Trichosporon species is one of the emerging mycoses in neutropenic patients, particularly when they are treated for haematological malignancy with cytotoxic and immunosuppressive chemotherapy. We report a 15-year-old boy with acute lymphoblastic leukaemia, whose Trichosporon mucoides infection was successfully treated with lipid complex amphotericin B plus 5-fluorocytosine.
منابع مشابه
Invasive Trichosporon Mucoides Infection in a Uremic Patient with Type 2 Diabetes Mellitus on Maintenance Hemodialysis
Invasive Trichosporon mucoides infections are very rare in uremic patients. They are almost exclusively seen in immunocompromised patients, especially in the setting of neutropenic patients with hematologic malignancies. We report the case of a 62-year-old uremic woman, without neutropenia and on maintenance hemodialysis for four years, who developed nosocomial disseminated Trichosporonosis muc...
متن کاملTrichosporon and trichosporonosis
Trichosporon is a genus of anamorphic fungi in the family Trichosporonaceae. All species of Trichosporon are yeasts with no known teleomorphs. Most are typically isolated from soil, but several species occur as a natural part of the skin microbiota of humans and other animals. Proliferation of Trichosporon yeasts in the hair can lead to an unpleasant but non-serious condition known as white pie...
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متن کاملTrichosporon faecale invasive infection in a patient with severe aplastic anemia: Efficacy of voriconazole and liposomal amphotericin B before neutrophil recovery
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متن کاملAmphotericin B and 5-fluorocytosine: in vitro effects on lymphocyte function.
The effects of amphotericin B, 5-fluorocytosine, and the combination of both drugs on lymphocyte function in vitro were investigated. Amphotericin B, alone or in combination with 5-fluorocytosine, significantly suppressed both spontaneous lymphocyte transformation and the response of lymphocytes to stimulation with streptokinase-streptodornase. 5-Fluorocytosine had no effect on spontaneous or a...
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ورودعنوان ژورنال:
- Mycoses
دوره 49 3 شماره
صفحات -
تاریخ انتشار 2006