Lacrimal Location of Sinus Histiocytosis (Destombes-Rosai-Dorfman Disease)
نویسندگان
چکیده
A 7-year-old West African male patient presented with recurrence of multiple cervical lymphadenopathy. Cervical node biopsy disclosed a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman-Destombes disease). During follow-up, the patient developed a left orbital mass corresponding to an enlarged lacrimal gland shown by CT. The histologic features of the gland were consistent with the diagnosis, and with steroid treatment, the gland decreased in size. Although rare, the diagnosis of sinus histiocytosis with massive lymphadenopathy has to be considered in cases of lacrimal gland enlargement.
منابع مشابه
Extra nodal Rosai Dorfman disease of nasal septal mucosa without lymphadenopathy
Rosai–Dorman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), a rare and usually self limiting disease, was originally described by Destombes in 1965. Subsequently; in 1969, it was characterized as a distinct clinicopathological disorder by Rosai and Dorfman. It is a pseudolymphomatous nonneoplastic lymphoproliferative disease of unknown etiology that presen...
متن کاملRosai-Dorfman Disease in a 23-Year-Old Patient
Rosai-Dorfman Disease (RDD) also known as Sinus Histiocytosis With Massive Lymphadenopathy (SHML) is a rare and benign nonLangerhans histiocytosis. First described in 1965 by Destombes [1] then in 1969 by Rosai and Dorfman, this disease is characterized by benign histiocytic proliferation with frequent lymphophagocytosis (emperipolesis) [2]. All ages are affected but most of the patients presen...
متن کاملCutaneous Rosai-Dorfman Disease Located on the Breast: Rapid Effectiveness of Methotrexate After Failure of Topical Corticosteroids, Acitretin and Thalidomide.
An erythematous cutaneous plaque on the breast with no signs of infection requires a skin biopsy to rule out dermal extension of an underlying mammary adenocarcinoma, primary skin tumour (e.g. angiosarcoma or malignant lymphoma) (1), or inflammatory lymphoedema of the breast (2). It can more rarely reveal location on the skin of systemic disease. Rosai-Dorfman disease (RDD), also known as sinus...
متن کاملRosai-Dorfman Disease: A Case Report and Literature Review
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. The diagnosis is based on immunohistochemistry. Its treatment is poorly defined but the prognosis is usually favorable. Here we report a 14 year old boy who presented with massive bilateral cervi...
متن کاملMyopic peripapillary sinkhole: prolapse of retinal nerve fiber layer and posterior vitreous into a sclerochoroidal hollow causing peripapillary choroidal thickening and cavitation.
1. Rosai J, Dorfman RF. Sinus histiocytosis with massive lymphadenopathy: a newly recognized benign clinicopathological entity. Arch Pathol. 1969;87 (1):63-70. 2. Foucar E, Rosai J, Dorfman R. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity. Semin Diagn Pathol. 1990;7(1):19-73. 3. Eisen RN, Buckley PJ, Rosai J. Immunophenotypic characterization of ...
متن کامل