Targeting in DBS
نویسنده
چکیده
WHAT IS DBS? ........................................................................................................................................... 2 History of DBS ....................................................................................................................................... 2 Hardware of DBS ................................................................................................................................... 3 Surgical Procedure of DBS ..................................................................................................................... 4 Mechanisms of DBS............................................................................................................................... 5 DBS vs. ablation ..................................................................................................................................... 7 WHAT ARE THE TARGETS IN DBS? ............................................................................................................ 8 Ventral Thalamic Nuclei ........................................................................................................................ 9 Subthalamic Nucleus ............................................................................................................................. 9 Globus Pallidus pars interna ............................................................................................................... 10 HOW TO TARGETING IN DBS? ................................................................................................................. 11 By brain atlas ....................................................................................................................................... 12 By visible surrounding anatomical landmarks .................................................................................... 14 By direct locating (SWI/7T MRI/DTI) ................................................................................................... 15 By microelectrode recordings ............................................................................................................. 16 By macro stimulation tests ................................................................................................................. 18 References .................................................................................................................................................. 20
منابع مشابه
Anatomical situation of the subthalamic nucleus (STN) from midcommissural point (MCP) in Parkinson\'s disease patients underwent deep brain stimulation (DBS): an MRI targeting study
Abstract Introduction: It is demonstrated that the degree of clinical improvement in Parkinson's disease (PD) achieved by deep brain stimulation (DBS) is largely dependent on the accuracy of lead placement. In addition, individual variability in the situation of subthalamic nucleus (STN) is responsible for spatial inter-individual fluctuations of the real patient's target. Objecti...
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Background First developed in France in 1987, Deep Brain Stimulation (DBS) is a neurosurgical intervention that involves the implantation of a brain pacemaker, which electrically stimulates specific brain nuclei.1 The FDA approved DBS for treatment for Essential Tremor in 1997, Parkinson’s Disease in 2002 and Dystonia in 2003.1 More recently, DBS has been indicated in management of neuropsychia...
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BACKGROUND Targeting in deep brain stimulation (DBS) relies heavily on the ability to accurately localize particular anatomic brain structures. Direct targeting of subcortical structures has been limited by the ability to visualize relevant DBS targets. METHODS AND RESULTS In this work, we describe the development and implementation, of a methodology utilized to create a three dimensional def...
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Deep brain stimulation (DBS) is a widely accepted therapy for medically refractory Parkinson's disease (PD). Both globus pallidus internus (GPi) and subthalamic nucleus (STN) stimulation are safe and effective in improving the symptoms of PD and reducing dyskinesias. STN DBS is the most commonly performed surgery for PD as compared to GPi DBS. Ventral intermediate nucleus (Vim) DBS is infrequen...
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