Guillain-Barré syndrome and SIADH in a patient with chronic lymphocytic leukemia.
نویسنده
چکیده
Guillain-Barre syndrome, an acute or subacute inflammatory demyelinating polyradiculoneuropathy, usually causes ascending paralysis, areflexia, and sensory disturbances. l A similar syndrome, more chronic and sometimes relapsing, has been called chronic inflammatory demyelinating polyneuropathy.2 Thought to have an immunologic cause, Guillain-Barre syndrome can be found in association with infections, vaccinations, and malignancies. The syndrome has been linked to carcinomas and to Hodgkin and non-Hodgkin lymphomas, and both Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy have been seen with the chemotherapy and other interventions associated with bone marrow transplantation.3 Guillain-Barre syndrome has, however, only rarely been reported in patients with chronic lymphocytic leukemia.4•s We report the occurrence of a painful, acute polyneuropathy, with features of Guillain-Barre syndrome and complicated by the syndrome of inappropriate antidiuretic hormone secretion, which affected an elderly woman who underwent chemotherapy for chronic lymphocytic leukemia.
منابع مشابه
Acute Polyneuropathy in Children with Acute Lymphocytic Leukemia: Case Report and Systemic Review of the Literature
Acute polyneuropathy in children with acute lymphoblastic leukemia is extremely rare, but its onset and association with Guillain-Barré syndrome presents a diagnostic challenge. We report a 5-year-old boy who presented with inability to walk during induction chemotherapy for acute lymphoblastic leukemia. Subsequently he developed painful penile erections, difficulty urinating and swallowing. Be...
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OBJECTIVE To report a case of severe Guillain-Barré syndrome in a 32-year old female patient diagnosed with acute lymphoblastic leukaemia who was on chemotherapy. CLINICAL PRESENTATION AND INTERVENTION The patient received chemotherapy including vincristine and steroids according to the Medical Research Council United Kingdom Acute Lymphoblastic Leukaemia-12 (MRC UKALL-12) protocol. On the 21...
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Background: Guillain-Barré syndrome is an autoimmune inflammatory disease, which manifests itself as an acute motor weakness of the organs, diagnosed as affecting the motor spinal nerve roots generally and causing muscle and motor weakness, the cause of this disease is the presence of active antibodies against the myelin sheath around the spinal nerve roots. Guillain-Barré syndrome is the most ...
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We report a 72-year-old female patient with diffuse large B cell non-Hodgkin's lymphoma (NHL) with previous treatment with standard chemotherapy presenting as an acute, ascending, sensorimotor polyneuropathy. Nerve conduction studies and lumbar puncture supported a rare, but ominous, axonal variant of Guillain-Barré Syndrome (GBS) known as acute motor and sensory axonal neuropathy (AMSAN), whic...
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ورودعنوان ژورنال:
- The Journal of the American Board of Family Practice
دوره 11 3 شماره
صفحات -
تاریخ انتشار 1998