Author's response to reviews Title: Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkers Authors:
نویسندگان
چکیده
Ewa Szalowska ([email protected]) Martijn Dijkstra ([email protected]) Marieke G.L. Elferink ([email protected]) Desiree Weening ([email protected]) Marcel de Vries ([email protected]) Marcel Bruinenberg ([email protected]) Annemieke Hoek ([email protected]) Han Roelofsen ([email protected]) Geny M.M. Groothuis ([email protected]) Roel J. Vonk ([email protected])
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Identification of specific gene expression after exposure to low dose ionizing radiation revealed through integrative analysis of cDNA microarray data and the interactome
Background: Accumulating reports suggest that the biological effects of low- and high- dose ionizing radiation (LDIR and HDIR) are qualitatively different and might cause different effects in human skin. Materials and Methods: To better understand the potential risks of LDIR, we analyzed three cDNA microarray datasets from the Gene Expression Omnibus database. Results: A pathway analysis showed...
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Lipopolysaccharide is a component of outer membrane of gram-negative bacteria involved in the pathogenic process leading to mastitis and metritis in dairy cattle. Additionally, LPS could be caused endometrium inflammation and implantation failure in many animal species. Based on economic importance of these diseases in dairy cattle industry, analysis of differential gene expression (DGE) and al...
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It has been shown that the renin-angiotensin system (RAS) plays key roles in the inflammation process. Imbalance in the oxidant-antioxidant system is one of the major causes of inflammation. In the present study, the effects of captopril on total and differential WBC, oxidative stress in systemic inflammation produced by lipopolysaccharide (LPS) were investigated. The rats were divided to: cont...
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Effects of thymol on non-alcholic hepatic liver induced with chronic immobility in rats
Abstract Background and Aim: Considering the role of oxidative stress on non-alcoholic fatty liver disease and changing lipid profiles, the antioxidant effect of plants and fruits on biochemical indicators was investigated. Thymol is a phenolic monoterpene that has antioxidant properties. According to the above, in this study, the effects of thymol on improving the symptoms of non-alcoholic fa...
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