Development of a flow method for the hydroboration/oxidation of olefins.
نویسندگان
چکیده
A method for the continuous preparation of alcohols by hydroboration/oxidation of olefins using flow techniques is described. The process allows the isolation of up to 120 mmol h(-1) of the desired alcohol in a very rapid manner with good functional group tolerance. The flow setup can be modified to perform a continuous extraction of the desired alcohol from the biphasic mixture produced by the reaction.
منابع مشابه
C5ob00170f 3871..3877 ++
A method for the continuous preparation of alcohols by hydroboration/oxidation of olefins using flow techniques is described. The process allows the isolation of up to 120 mmol h−1 of the desired alcohol in a very rapid manner with good functional group tolerance. The flow setup can be modified to perform a continuous extraction of the desired alcohol from the biphasic mixture produced by the r...
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 13 شماره
صفحات -
تاریخ انتشار 2015