In vitro antimycobacterial activity of 5-chloropyrazinamide.

نویسندگان

  • M H Cynamon
  • R J Speirs
  • J T Welch
چکیده

5-Chloropyrazinamide and 5-chloropyrazinoic acid were evaluated for in vitro activity against Mycobacterium tuberculosis, Mycobacterium bovis, and several nontuberculous mycobacteria by a broth dilution method. 5-Chloropyrazinamide was more active than pyrazinamide against all organisms tested. It is likely that this agent has a different mechanism of action than pyrazinamide.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 42 2  شماره 

صفحات  -

تاریخ انتشار 1998