Analysis of chemical composition of Chrysanthemum indicum flowers by GC/MS and HPLC

Chrysanthemum indicum flower is a traditional Chinese medicine with strong aroma and many previous studies focused on its essential oil. GC/MS and HPLC were used to determine its volatiles, flavonoids and flavonoid glycosides. Sixty three volatiles were detected and the abundant volatiles included 2,6,6trimethyl-bicyclo[3.1.1]hept-2-en-4-ol, 2-(2,4-hexadiynylidene)-1,6-dioxaspiro[4.4]non-3-ene, germacrene D, á-neoclovene, eucalyptol, á-pinene. Ten flavonoids were identified. Quercitrin, myricetin and luteolin7-glucoside were abundant flavonoids. The bioactivities of the abundant components in Chrysanthemum indicum flower were discussed. It is considered that Chrysanthemum indicum flower is a good source of natural quercitrin and myricetin, which is significant for the development of potential pharmaceuticals.