An Important Problem: Posttransplant Focal Segmental Glomerulosclerosis Recurrence and Plasmapheresis Önemli Bir Problem: Transplantasyon Sonrası Fokal Segmental Glomeruloskleroz Nüksü ve Plazmaferez
نویسندگان
چکیده
1 İstanbul Research and Training Hospital, Department of Nephrology, İstanbul, Turkey 2 Bezmialem Vakıf Universty, Faculty of Medicine, Department of Nephrology, İstanbul, Turkey 3 Fatih Private Dialysis Center, Department of Nephrology, İstanbul, Turkey 4 İstanbul Universty, İstanbul Faculty of Medicine, Department of Nephrology, İstanbul, Turkey 5 Şevket Yılmaz Research and Training Hospital, Department of Nephrology, İstanbul, Turkey doi: 10.5262/tndt.2015.1001.06
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Treatment of Recurrent Focal Segmental Glomerulosclerosis in Pediatric Kidney Transplant Recipients: Effect of Rituximab
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A 26-year-old male experienced a recurrence of idiopathic focal segmental glomerulosclerosis (iFSGS) after his second renal transplant. Reduction of proteinuria was rapidly induced by plasmapheresis (PP) and the patient has remained in remission with a once-weekly PP regimen, which has now been continued for >3½ years. We were also able to induce remission of iFSGS in this patient by treatment ...
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Material and Method: in a cross-sectional study, 50 patients with biopsy-proven primary focal segmental glomerolusclerosis were recruited. The proportion of globally and segmentally sclerosed glomeruli was determined during the first histopathological examination of renal biopsy specimens. Correlations of these variables with on admission serum level of creatinine and its clearance rate were in...
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