On Transient Infections with Leishmania Donovani in Man and Animals
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منابع مشابه
Cutaneous Lesions Following Inoculation of Live Culture of Leishmania Donovani in Man
produced in man by inoculation of cultures of Leishmania tropica. Cutaneous inoculation of Leishmania donovani from spleen puncture material from a case of kala-azar, however, is reported to have ' apparently produced kala-azar in a man' but on two occasions accidental inoculation of spleen puncture material from cases of kala-azar was without any effect (Napier, 1927). Recently, Terry et al. (...
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Surface phosophoglycans such as lipophosphoglycan (LPG) or proteophosphoglycan (PPG) and glycosylinositol phospholipids (GIPLs) modulate essential interactions between Leishmania and mammalian macrophages. Phosphoglycan synthesis depends on the Golgi GDP-mannose transporter encoded by LPG2. LPG2-null (lpg2(-)) Leishmania major cannot establish macrophage infections or induce acute pathology, wh...
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