Therapeutic hypothermia following perinatal asphyxia.
نویسندگان
چکیده
Well constructed and carefully analysed trials of hypothermic neural rescue therapy for infants with neonatal encephalopathy have recently been reported. The data suggest that either selective head cooling or total body cooling reduces the combined chance of death or disability after birth asphyxia. However, as there are still unanswered questions about these treatments, many may still feel that further data are needed before health care policy can be changed to make cooling the standard of care for all babies with suspected birth asphyxia.
منابع مشابه
Therapeutic Hypothermia Modifies Perinatal Asphyxia-Induced Changes of the Corpus Callosum and Outcome in Neonates
UNLABELLED WHAT IS KNOWN ABOUT THIS SUBJECT?: Diffusion-weighted MRI has demonstrated changes in the corpus callosum of term neonates with perinatal asphyxia. The severity of cerebral changes demonstrated using diffusion-weighted MRI is difficult to assess without measuring values of the Apparent Diffusion Coefficient (ADC). WHAT IS NEW?: ADC values of the anterior part of the corpus callosum a...
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Our objective was to estimate the effect of therapeutic hypothermia on platelet count in neonates after perinatal asphyxia. We performed a retrospective case control study of all (near-) term neonates with perinatal asphyxia admitted between 2004 and 2012 to our neonatal intensive care unit. All neonates treated with therapeutic hypothermia were included in this study (hypothermia group) and co...
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Background: Asphyxia is a perinatal accident with a high mortality rate, therapeutic hypothermia in both head or whole body was suggested as effective therapeutic methods. In this study, we compare these methods in neonates with asphyxia.Methods and Materials: 16 neonates with asphyxia in two hospitals including Alzahra(head hypothermia) and Taleghani hospital (total body hypothermia) went unde...
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perinatal asphyxia using the cardiac biomarkers cTnI and brain natriuretic peptide (BNP). Troponin T and I are sensitive markers of myocardial injury following a perinatal hypoxic-ischaemia insult. BNP is a marker of ventricular wall stress secondary to myocardial dysfunction [8] . cTnI and BNP were collected before the start of hypothermia, at 24 and 48 h after birth, and after rewarming. BNP ...
متن کاملHypothermia for perinatal asphyxial encephalopathy.
BACKGROUND Perinatal asphyxial encephalopathy occurs in 1 per 1000 live births and is associated with high mortality and morbidity. Therapeutic hypothermia increases intact survival and improves neurodevelopmental outcome in survivors. AIMS To evaluate (i) the opinion and practice of therapeutic hypothermia as a therapy for moderate to severe perinatal asphyxial encephalopathy amongst Swiss n...
متن کاملTherapeutic hypothermia for hypoxic-ischemic encephalopathy: challenges during transfer and global perspectives.
Perinatal asphyxia resulting in hypoxic--ischemic encephalopathy (HIE) occurs in 1--2/1000 live births in high income countries, and 10--20/1000 in lowand middleincome countries (LMICs). Worldwide, HIE affects around 2.7 million newborn infants, of whom 690,000 die. Over half of survivors go on to develop cerebral palsy, epilepsy, and other forms of lifelong neurological disability. The adoptio...
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ورودعنوان ژورنال:
- Archives of disease in childhood. Fetal and neonatal edition
دوره 91 2 شماره
صفحات -
تاریخ انتشار 2006