CRVO without anti-cardiolipin antibody

نویسندگان

  • Seigo Korematsu
  • Hironori Goto
  • Chika Gotoh
  • Ryoko Ohki
  • Toshiaki Kubota
  • Tatsuro Izumi
چکیده

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Anti-Cardiolipin and Anti-Neutrophil Cytoplasmic Antibodies in Iranian Patients with Behcet's Disease

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Anti-cardiolipin antibody from a patient with antiphospholipid syndrome (APS) recognizes only an epitope expressed by cardio- lipin/ 2-glycoprotein-I ( 2GPI) complex and induces APS

Objective As the antiphospholipid syndrome (APS) is characterized by antibodies which bind negatively charged phospholipids either directly or mainly through different target epitopes located on the beta-2-glycoprotein-I ( 2GPI) molecule, the aim of this study is to describe an additional target epitope for anti-cardiolipin binding. Methods The binding characteristics of affinity purified anti-...

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تاریخ انتشار 2014