Hidradenitis suppurativa and Crohn's disease: two cases that support an association.
نویسندگان
چکیده
An association between Crohn's disease and hidradenitis suppurativa has been suggested. The presence of Crohn's disease generally precedes the diagnosis of hidradenitis suppurativa. We present two new cases in which hidradenitis lesions developed before Crohn's disease, suggesting an overlap and supporting an association. Furthermore, in one of these cases, treatment with infliximab resulted in marked improvement in both the Crohn's disease and hidradenitis suppurativa.
منابع مشابه
Probable association between hidradenitis suppurativa and Crohn's disease: significance of epithelioid granuloma.
Hidradenitis suppurativa affects apocrine gland-bearing areas of skin and may produce perianal lesions clinically indistinguishable from the cutaneous manifestations of Crohn’s disease1, suggesting an association between the two diseases1–3. A recent histological study3 of hidradenitis suppurativa described epithelioid granulomas in 10 per cent of cases. Some of these patients had systemic gran...
متن کاملTwo Cases of Paradoxical Hidradenitis Suppurativa while on Adalimumab
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by recurring abscesses, nodules, and fistulas predominantly in the groin and axillae. The association between HS and Crohn's disease (CD) has been well documented. Tumor necrosis factor (TNF) inhibitors have shown to be effective in treating both HS and CD. We report 2 patients who developed HS while on TNF inhi...
متن کاملTreatment of hidradenitis suppurativa with infliximab in a patient with Crohn's disease.
BACKGROUND Hidradenitis suppurativa is a chronic, inflammatory, scarring disease characterized by recurrent flares. Recently, a group of 'autoinflammatory disorders' has been described. These disorders are characterized by recurrent inflammatory episodes not mediated by autoantibodies or antigen-specific T-cells. Some of these autoinflammatory disorders have been successfully treated with anti-...
متن کاملAdalimumab treatment for hidradenitis suppurativa associated with Crohn's disease.
Hidradenitis suppurativa (HS) is a chronic, inflammatory disease characterized by recurring abscesses, nodules, and fistulas predominantly in the area of the groin and axillae. The association between HS and Crohn's disease (CD) has already been documented. We report on a case of a patient with CD associated HS, refractory to multiple local and systemic agents.A complete resolution of both dise...
متن کاملMicrobial profile and antibiotic susceptibility of bacteria isolated from patients with hidradenitis suppurativa
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of unknown etiology. There is evidence that bacteria may contribute to initiating the inflammatory response in HS patients. To date, data on bacteria found in HS lesions and their resistance rates are rare. Methods: The results of bacterial cultures and antibiotic susceptibility of the isolated bacteria obtained fr...
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ورودعنوان ژورنال:
- Acta dermatovenerologica Alpina, Pannonica, et Adriatica
دوره 19 3 شماره
صفحات -
تاریخ انتشار 2010