Norcyperone, a novel skeleton norsesquiterpene from Cyperus rotundus L.

نویسندگان

  • Yan Xu
  • Hong-Wu Zhang
  • Chang-Yuan Yu
  • Yang Lu
  • Ying Chang
  • Zhong-Mei Zou
چکیده

A novel norsesquiterpene, named norcyperone (1), and three known compounds: (-)-clovane-2,9-diol (2), rosenonolactone (3), and 5 alpha,8 alpha-epidioxy-(20S,22E,24R)-ergosta-6,22-dien-3beta-ol (4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1]undecane-5 alpha, 8 alpha-epoxy-3-one on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR, MS experiments, and single-crystal X-ray diffraction. This is the first report of a 8,11,11-trimethyl- bicyclo[5.3.1]undecane-3-one type norsesquiterpene with a tetrahydrofuran ring at C-5 and C-8.

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عنوان ژورنال:
  • Molecules

دوره 13 10  شماره 

صفحات  -

تاریخ انتشار 2008