Dysphagia in Parkinson’s Disease

نویسندگان

  • Rosane Sampaio Santos
  • Carlos Henrique Ferreira Camargo
  • Edna Márcia da Silva Abdulmassih
  • Hélio Afonso Ghizoni Teive
چکیده

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Dysphagia is a relevant symptom in Parkinson’s disease, whose pathophysiology is poorly understood. It is mainly attributed to degeneration of brainstem nuclei. However, alterations in the cortical contribution to deglutition control in the course of Parkinson’s disease have not been investigated. Here, we sought to determine the patterns of cortical swallowing processing in patients with Parki...

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The aim of this review is to present an update of the prevalence, impact and management challenges of dysphagia in Parkinson’s disease. In the last 5 years, the prevalence of dysphagia in Parkinson’s disease (PD) has been reported with a wide range of values in the literature. The dysphagia prevalence ranged from 11% to 100% of the patients with PD. This variation, generally, depended on the di...

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Parkinson's disease (PD) is a chronic, neurodegenerative movement disorder that typically affects elderly patients. Swallowing disorders are highly prevalent in PD and can have grave consequences, including pneumonia, malnutrition, dehydration and mortality. Neurogenic dysphagia in PD can manifest with both overt clinical symptoms or silent dysphagia. Regardless, early diagnosis and objective f...

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Purpose: We compared serum substance P (SP) levels in underlying diseases and dysphagia, or its absence, in patients with cerebrovascular disease, neurodegenerative disease or Alzheimer’s disease, to investigate the relationship between dysphagia and serum SP in chronic central nervous disease. Methods: Subjects comprised 94 patients admitted to a hospital or nursing home during the 5 years bet...

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تاریخ انتشار 2017