Low-dose dapsone in chronic idiopathic urticaria: preliminary results of an open study.

Sir, Chronic idiopathic urticaria (CIU) is defined as the occurrence of wheals on most days for more than 6 weeks in the absence of any known causative or triggering agents (1). Most cases of chronic urticaria are classified as ‘idiopathic’, despite intense efforts to determine any aetiological factor, and require long-term treatment with H1-receptor antagonists, which are the first-line approach to uncomplicated forms (2). Here we present our cumulative experience with dapsone in some cases of severe refractory CIU.