Oral contraceptives, venous thromboembolism, and the courts.

Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data

OBJECTIVE To compare the risk of non-fatal venous thromboembolism in women receiving oral contraceptives containing drospirenone with that in women receiving oral contraceptives containing levonorgestrel. DESIGN Nested case-control and cohort study. SETTING The study was based on information from PharMetrics, a United States based company that collects information on claims paid by managed ...

CPMP PUBLIC ASSESSMENT REPORT Combined oral contraceptives and venous thromboembolism

Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9

OBJECTIVE To assess the risk of venous thromboembolism from use of combined oral contraceptives according to progestogen type and oestrogen dose. DESIGN National historical registry based cohort study. SETTING Four registries in Denmark. PARTICIPANTS Non-pregnant Danish women aged 15-49 with no history of thrombotic disease and followed from January 2001 to December 2009. MAIN OUTCOME M...

Risk of venous thromboembolism in women with polycystic ovary syndrome: a population-based matched cohort analysis.

BACKGROUND There is an increased risk of venous thromboembolism among women taking oral contraceptives. However, whether there is an additional risk among women with polycystic ovary syndrome (PCOS) is unknown. METHODS We developed a population-based cohort from the IMS LifeLink Health Plan Claims Database, which includes managed care organizations in the United States. Women aged 18-46 years...

Effect of 1995 pill scare on rates of venous thromboembolism among women taking combined oral contraceptives: analysis of general practice research database.

OBJECTIVE To compare the incidence of venous thromboembolism among women taking combined oral contraceptives before and after the October 1995 pill scare. DESIGN Analysis of General Practice Research Database. SETTING United Kingdom, January 1993 to December 1998. SUBJECTS Women aged 15-49 taking combined oral contraceptives. MAIN OUTCOME MEASURES Incidence of venous thromboembolism. ...