Rieger's anomaly: a 42-year follow-up.

Rieger (1935) described two patients with striking anomalies of iris and angle. Each patient had glaucoma associated with hypoplasia of the anterior leaf of the iris, corectopia, and pseudopolycoria. There were iris adhesions both to the posterior surface of the cornea and to posterior embryotoxon, together with mesodermal tissue in the angle (Rieger, 1935). Later a number of systemic abnormalities were added, including oligoor hypodentia, with abnormal enamel formation and maxillary hypoplasia (Rieger, 1941). Rieger called the condition dysgenesis mesodermalis cornae et iridis, to which his name was linked. This report presents the findings for the first patient in Rieger's report who presented for reexamination 42 years later.