Synthesis and olfactory evaluation of bulky moiety-modified analogues to the sandalwood odorant Polysantol.

نویسندگان

  • Laura Chapado
  • Pablo J Linares-Palomino
  • Concepción Badía
  • Sofía Salido
  • Manuel Nogueras
  • Adolfo Sánchez
  • Joaquín Altarejos
چکیده

Five new bulky moiety-modified analogues of the sandalwood odorant Polysantol have been synthesized by aldol condensation of appropriate aldehydes with butanone, deconjugative alpha-methylation of the resulting alpha,beta-unsaturated ketones, and reduction of the corresponding beta,gamma-unsaturated ketones. The final compounds were evaluated organoleptically and one of them seemed to be of special interest for its natural sandalwood scent.

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عنوان ژورنال:
  • Molecules

دوره 14 8  شماره 

صفحات  -

تاریخ انتشار 2009