Correction: A Common Polymorphism within the IGF2 Imprinting Control Region Is Associated with Parent of Origin Specific Effects in Infantile Hemangiomas.
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The images for Figs 1 and 2 are incorrectly switched. The image that appears as Fig 1 should be Fig 2, and the image that appears as Fig 2 should be Fig 1. The Figure captions appear in the correct order. Please see the corrected Figs 1 and 2 here. open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
A Common Polymorphism within the IGF2 Imprinting Control Region Is Associated with Parent of Origin Specific Effects in Infantile Hemangiomas
Infantile hemangioma (IH) is the most common tumor of the pediatric age group, affecting up to 4% of newborns ranging from inconsequential blemishes, to highly aggressive tumors. Following well defined growth phases (proliferative, plateau involutional) IH usually regress into a fibro-fatty residuum. Despite the high prevalence of IH, little is known regarding the pathogenesis of disease. A rep...
متن کاملGenomic imprinting of IGF2 is maintained in infantile hemangioma despite its high level of expression.
Hemangioma, the most common tumor of infancy, is characterized by rapid growth and slow regression. Increased mRNA expression of insulin-like growth factor 2 (IGF2) has been detected in the proliferating phase by cDNA microarray analysis, but the underlying mechanism causing the increase remains unknown. Here, using quantitative real-time polymerase chain reaction (PCR) and immunohistochemistry...
متن کاملI-50: Embryo Loss Due to Epigenetic Anomaliesin the Male Germ Line: Role of Estrogen
Background: To investigate if aberrant methylation and expression of imprinted genes of the Igf2-H19 locus in the spermatozoa and embryos could be a paternal epigenetic factor involved in early embryo loss To elucidate the role of estrogen in acquisition of the imprinting at the Igf2-H19 locus during spermatogenesis Materials and Methods: Adult male rats of Holtzman strain were administered tam...
متن کاملGWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.
Imprinting control regions (ICRs) play a fundamental role in establishing and maintaining the non-random monoallelic expression of certain genes, via common regulatory elements such as non-coding RNAs and differentially methylated regions (DMRs) of DNA. We recently surveyed DNA methylation levels within four ICRs (H19-ICR, IGF2-DMR, KvDMR, and NESPAS-ICR) in whole-blood genomic DNA from 128 mon...
متن کاملA 6-Month-Old Girl with Infantile Hemangioma of Left Lower Limb, a Case Report
Introduction: Hemangiomas are the most common tumors of infancy and infantile hemangiomas are the most common vascular tumors. The etiology of this tumor is unknown. Hemangiomas commonly occur in the skin followed by the deep tissues (intramuscular) and rarely within bones. Case Presentation: Hereby, the case of a 6-month-old girl whose whole left lower limb f...
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ورودعنوان ژورنال:
- PloS one
دوره 10 11 شماره
صفحات -
تاریخ انتشار 2015