Update on myelodysplastic syndrome.
نویسندگان
چکیده
Myelodysplastic Syndrome (MDS) is a bone marrow stem cell disorder, most commonly occurring in patients over 60 years old, characterized by cytopenias, bone marrow morphologic changes and cytogenetic abnormalities. Risks of MDS include infection, anemia, bleeding and transformation to Acute Myelogenous Leukemia (AML). Older adults, at higher risk, present a treatment challenge due to atypical presentation, multiple co-morbidities, and increased risk of adverse effects from treatment.
منابع مشابه
Range Determination of Antigen Expression in Myeloid, Erythroid and Lymphoid Cell Lineages among Patients with Myelodysplastic Syndrome
Background: Myelodysplastic syndrome is a mixed clonal disorder of bone marrow progenitor cells. Understanding the pattern of the different lineage-specific, immature, and mature markers in myelodysplastic syndrome will help in setting-up the frame of reference to diagnose. Patients and Methods: We compared 60 bone marrow samples from 30 newly-diagnosed patients with myelodysplastic syndrome ...
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عنوان ژورنال:
- Medicine and health, Rhode Island
دوره 92 9 شماره
صفحات -
تاریخ انتشار 2009