Comparative proteomic analysis of tear fluid versus nasal mucus in allergic rhinitis patients and healthy controls
نویسندگان
چکیده
Background Allergy is a common disorder in the western world with a prevalence of 15% to 20%. The combination of ocular symptoms in patients with allergic rhinitis occurs frequently. Nasal mucus for the nasal epithelium and tear fluid for the eye are the first defence barrier against various pathogens including aeroallergens. Little is known about the nasal mucus and particularly about the tear fluid proteome. The aim of the study was to analyse both body fluids on a proteome level and detect possible impact of its proteins in the pathophysiology in allergic rhinoconjunctivitis.
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