Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae: The First Reported Case in South Korea

نویسندگان

  • Suk Hyeon Jeong
  • Su-Young Kim
  • Hyun Lee
  • Jun Soo Ham
  • Keum Bit Hwang
  • Subin Hwang
  • Sun Hye Shin
  • Myung Jin Chung
  • Seung Heon Lee
  • Sung Jae Shin
  • Won-Jung Koh
چکیده

This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.

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عنوان ژورنال:

دوره 78  شماره 

صفحات  -

تاریخ انتشار 2015