Generation of OH initiated by interaction of Fe and Cu with dioxygen; comparison with the Fenton chemistry

نویسندگان

  • Norbert K. Urbañski
  • Andrzej Berêsewicz
چکیده

Iron and copper toxicity has been presumed to involve the formation of hydroxyl radical ( . OH) from H2O2 in the Fenton reaction. The aim of this study was to verify that Fe 2+ -O2 and Cu + -O2 chemistry is capable of generating . OH in the quasi physiological environment of Krebs-Henseleit buffer (KH), and to compare the ability of the Fe 2+ -O2 system and of the Fenton system (Fe 2+ + H2O2) to produce . OH. The addition of Fe 2+

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Generation of *OH initiated by interaction of Fe2+ and Cu+ with dioxygen; comparison with the Fenton chemistry.

UNLABELLED Iron and copper toxicity has been presumed to involve the formation of hydroxyl radical (*OH) from H2O2 in the Fenton reaction. The aim of this study was to verify that Fe2+-O2 and Cu+-O2 chemistry is capable of generating *OH in the quasi physiological environment of Krebs-Henseleit buffer (KH), and to compare the ability of the Fe2+-O2 system and of the Fenton system (Fe2+ + H2O2) ...

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تاریخ انتشار 2001