The motor protein myosin 1G functions in FccR-mediated phagocytosis
نویسندگان
چکیده
Anna E. Dart*, Sylvain Tollis, Michael D. Bright, Gad Frankel and Robert G. Endres Division of Molecular Biosciences, Imperial College, London SW7 2AZ, UK Centre for Integrative Systems Biology and Bioinformatics, Imperial College, London SW7 2AZ, UK Division of Cell and Molecular Biology, Imperial College, London SW7 2AZ, UK Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ, UK
منابع مشابه
The motor protein myosin 1G functions in FcγR-mediated phagocytosis.
Phagocytosis is the force-dependent complex cellular process by which immune cells engulf particles. Although there has been considerable progress in understanding ligand-receptor-induced actin polymerisation in pushing the membrane around the particle, significantly less is known about how localised contractile activities regulate cup closure in coordination with the actin cytoskeleton. Herein...
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Phagocytosis is required for proliferation and pathogenesis of Entamoeba histolytica and erythrophagocytosis is considered to be a marker of invasive amoebiasis. Ca²⁺ has been found to play a central role in the process of phagocytosis. However, the molecular mechanisms and the signalling mediated by Ca²⁺ still remain largely unknown. Here we show that Calmodulin-like calcium binding protein Eh...
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