Comparison of thyrotropin-receptor antibodies measured by four commercially available methods with a bioassay that uses Fisher rat thyroid cells.

Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. Identification of a novel 17,000-Dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercal-cemia of malignancy. Synthetic human parathyroid hormone-like protein stimulates bone resorp-tion and causes hypercalcemia in rats. The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17/2.8 cells. a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. hormone-related protein (PTHrP)-(1-139) isoform is efficiently secreted in vitro and enhances breast cancer metastasis to bone in vivo. Structure of the 5Ј flanking region of the gene encoding human parathyroid-hormone-related protein (PTHrP). Identification of an upstream promoter of the human parathyroid hormone-related peptide gene. characterization of a GC-rich promoter of the human parathyroid hormone-related peptide gene. Cell-specific and regulator-induced promoter usage and messenger ribonucleic acid splicing for para-thyroid hormone-related protein. Alternative promoter usage and mRNA splicing pathways for parathyroid hormone-related protein in normal tissues and tumours. reverse transcription-PCR quantification of vascular endothelial growth factor (VEGF) splice variants by LightCycler technology. Activation of PTHrP gene expression in squamous carcinoma cell lines by mutant isoforms of the tumor suppressor p53. Quantification of parathyroid hormone-related protein mRNA by competitive PCR and time-resolved lan-thanide fluorometry. The parathyroid hormone-related protein (PTHrP) gene: use of downstream TATA promotor and PTHrP 1–139 coding pathways in primary breast cancers vary with the occurrence of bone metastasis. Regulation of parathyroid hormone-related protein gene expression in murine keratino-cytes by E1A isoforms: a role for basal promoter and Ets-1 site. factor ␤ regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergism. Differential expression of RNA transcripts encoding unique carboxy-terminal sequences of human parathyroid hormone related peptide. regulation of the parathyroid hormone-related peptide gene by glucocorticoids and vitamin D in a human C-cell line. Regulation of parathyroid hormone-related peptide gene expression by cycloheximide. AB, et al. Effect of transforming growth factor-␤1 on parathyroid hormone-related protein secretion and mRNA expression by normal human keratino-cytes in vitro. Quantification of thyrotropin-receptor antibodies is important in the diagnosis and management of patients with Graves disease (1). Antibodies with stimulating activity (TSI) have traditionally been detected in bioassays that measure their effect on cloned rat thyroid cells (FRTL-5) or on …