Zebrafish housing, husbandry, health, and care: IACUC considerations.
نویسنده
چکیده
The articles in this issue review pertinent and specific information about infectious and noninfectious disease, housing system design and function, husbandry practices and techniques, and Internet resources as they specifically relate to zebrafish (Danio rerio). This article explores aspects that members of institutional animal care and use committees, husbandry care staff, physical plant personnel, veterinarians, principal investigators, and research personnel should consider with regard to the appropriate and necessary care and use of this unique fish model in a teaching, laboratory, or research setting. This information is designed to enhance understanding and facilitate collegial discussions to inform decision making about zebrafish care and use at various institutions or facilities.
منابع مشابه
IACUC Considerations for the Use of Livestock in Translational Research.
Through its program oversight function, the institutional animal care and use committee (IACUC) plays a central role in ensuring the humane use and care of animals in research. To be effective in this role, the IACUC requires explicit knowledge of the species for which it bears oversight responsibility. Owing to a variety of species-specific factors, such as their relatively large size and rang...
متن کاملRegular Care and Maintenance of a Zebrafish (Danio rerio) Laboratory: An Introduction
This protocol describes regular care and maintenance of a zebrafish laboratory. Zebrafish are now gaining popularity in genetics, pharmacological and behavioural research. As a vertebrate, zebrafish share considerable genetic sequence similarity with humans and are being used as an animal model for various human disease conditions. The advantages of zebrafish in comparison to other common verte...
متن کاملPreparing for a semiannual IACUC inspection of a satellite zebrafish (Danio rerio) facility.
Institutions worldwide have experienced a rapid growth in the use of zebrafish as a research model for a variety of molecular and genetic studies of vertebrate development. This expansion in zebrafish research essentially has outpaced the establishment of specific recommendations for the care and use of fish in research. In some cases, this situation has created a dilemma where an Institutional...
متن کاملReport of a Meeting on Contemporary Topics in Zebrafish Husbandry and Care
A meeting on Contemporary Topics in Zebrafish Husbandry and Care was held in the United Kingdom in 2014, with the aim of providing a discussion forum for researchers, animal technologists, and veterinarians from academia and industry to share good practice and exchange ideas. Presentation topics included protocols for optimal larval rearing, implementing the 3Rs (replacement, reduction, and ref...
متن کاملEnsuring reproducibility and ethics in animal experiments reporting in Korea using the ARRIVE guideline
The aim of this study is to evaluate the reporting quality of animal experiments in Korea using the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guideline developed in 2010 to overcome the reproducibility problem and to encourage compliance with replacement, refinement and reduction of animals in research (3R's principle). We reviewed 50 papers published by a Korean research grou...
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ورودعنوان ژورنال:
- ILAR journal
دوره 53 2 شماره
صفحات -
تاریخ انتشار 2012