del(13q) in myeloid malignancies
نویسندگان
چکیده
Note Chromosomal deletions are among the most common genetic events observed in hematologic malignancies; loss of genetic materiel is regarded as a hallmark of putative tumor suppressor gene localization. Deletions 13q occurs in lymphoid neoplasias: see del(13q) in non-Hodgkin's lymphoma and del(13q) in chronic lymphoproliferative diseases. In myeloid disorders, the most frequently reported deletions affect chromosomes 5, 7 and 20 (del(5q), del(7q), and del(20q), but deletion of chromosome 13 is another relatively common aberration.
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