Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform.

نویسندگان

  • Tatsuro Goda
  • Miyuki Tabata
  • Mai Sanjoh
  • Mai Uchimura
  • Yasuhiko Iwasaki
  • Yuji Miyahara
چکیده

We developed a new building block for a protein- and cell-repellant self-assembled monolayer (SAM) from 2-methacryloyloxyethyl phosphorylcholine (MPC) via a simple Michael-type addition to one mercapto group in alkanedithiol. The thiolated MPC can enable functionalization of a noble metal electrode to minimize noise signal in biosensing.

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عنوان ژورنال:
  • Chemical communications

دوره 49 77  شماره 

صفحات  -

تاریخ انتشار 2013